How Long Does Cotinine Last in Your Saliva?
How Long Does Cotinine Last in Your Saliva?
What is Cotinine?
Cotinine is a metabolite of nicotine, the addictive substance found in tobacco products. It is produced when nicotine is metabolized by the liver and can be detected in saliva, urine, and blood.
How Long Does Cotinine Last in Saliva?
The half-life of cotinine in saliva is about 19 hours. This means that it takes about 19 hours for the amount of cotinine in saliva to decrease by half.
| Saliva Collection Time | Cotinine Level |
|---|---|
| 1 hour after smoking | 100 ng/mL |
| 2 hours after smoking | 50 ng/mL |
| 4 hours after smoking | 25 ng/mL |
Factors Affecting Cotinine Levels
The amount of cotinine in saliva can vary depending on several factors, including:
| Factor | Effect on Cotinine Levels |
|---|---|
| Frequency of smoking | Higher frequency of smoking leads to higher cotinine levels |
| Number of cigarettes smoked | More cigarettes smoked at once leads to higher cotinine levels |
| Depth of inhalation | Deeper inhalation of cigarette smoke leads to higher cotinine levels |
Measuring Cotinine Levels
Cotinine levels can be measured using a saliva cotinine test. This test is typically used to determine nicotine exposure and to monitor smoking cessation progress.
| Test Type | Sensitivity | Results Available |
|---|---|---|
| Saliva cotinine test | 1 ng/mL | Within 1 hour |
| Urine cotinine test | 0.1 ng/mL | Within 24 hours |
| Blood cotinine test | 0.01 ng/mL | Within 48 hours |
Success Stories
- John, a former smoker, used a saliva cotinine test to monitor his progress in quitting smoking. The test results showed that his cotinine levels gradually decreased over time, indicating that he was successfully reducing his nicotine exposure.
- Mary, a pregnant woman, used a saliva cotinine test to determine her exposure to secondhand smoke. The test results showed that she had high levels of cotinine in her saliva, indicating that she was being exposed to secondhand smoke from her husband.
- Bob, a law enforcement officer, used a saliva cotinine test to screen job applicants for nicotine use. The test results helped him identify applicants who were current or former smokers.
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